Clinician-led · backed by a decade of science

The clinical ground-truth layer for healthcare

Spae builds CADEN — the engine that ascertains and validates the clinical states that revenue, quality, outcomes, and research depend on.

See how CADEN works
In live deployment at top hospitals in the US Clinician-native workflow
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Core technology

CADEN turns messy health data into validated clinical states.

The Clinical condition Ascertainment & Detection ENgine resolves fragmented, longitudinal data into interpretable clinical states — the missing ground truth layer between health data and everything built on it.

Progress Notes — Inpatient
CADEN · clinical state detected
# Acute Blood Loss Anemia
The patient is diagnosed with acute blood loss anemia, supported by:
An acute, significant decline in hemoglobin from 13.0 g/dL (08/07/2025 04:33) to 10.0 g/dL (08/07/2025 16:20) over 12 hours.
A nadir hemoglobin of 10.0 g/dL (08/07/2025 16:20) is consistent with anemia.
The clinical picture is consistent with acute blood loss anemia. The patient is managed with close monitoring, including serial examinations, laboratory evaluations, and diagnostic testing as indicated.
Attending Physician · 08/07/2025, 17:11Validated
A validated clinical state, surfaced with its supporting evidence — right inside the clinician's native workflow.
Platform

One engine. A growing line-up of Spae applications.

Point solutions optimize a single workflow. CADEN creates reusable clinical intelligence that powers many.

Healthcare Operation

Revenue Intelligence

Evidence-backed condition identification and automated documentation in the native workflow — optimal revenue capture, no added burden.

Healthcare Operation

Quality Intelligence

Evidence-based ascertainment of complications and quality outcomes — accurate reporting, automatically.

Healthcare Operation

Clinical Surveillance

Prospective detection of clinical deterioration and high-risk clinical states.

Infrastructure

Healthcare AI Infrastructure

Validated clinical states, labels, outcomes, and APIs — the ground-truth layer for healthcare AI.

Engaged on implementation with leading U.S. health systems — streamlining documentation, revenue capture, and quality reporting without added administrative burden.

Insights

Announcements, News, and Perspectives from Spae

Spae

Leading clinical state intelligence to transform healthcare operations and empower health AI

For health systems, investors, and partners who believe health data deserves ground truth.

See how CADEN works
Clinical state intelligence for healthcare operations and AI.
© Spae